Frequently Asked Questions (FAQs)

These questions are for patients who are considering RAYOS and for patients who have been prescribed RAYOS. This does not replace talking with your doctor. Only your doctor can offer information that is specific to your own health history. Always follow your doctor’s instructions.

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RAYOS is an anti-inflammatory medicine that can be used to treat many different conditions, including rheumatologic diseases such as rheumatoid arthritis (RA) and polymyalgia rheumatica (PMR).

It is also used to treat certain allergic, skin, stomach, intestinal, blood, eye, nerve, kidney, breathing, rheumatologic, and specific infectious diseases or conditions, and certain conditions related to organ transplantation.

RAYOS can be used in the treatment of certain endocrine conditions and to ease the symptoms, including pain, of certain cancer conditions as well.

For a complete list of indications for RAYOS, please see the full Prescribing Information.

Common side effects of RAYOS may include water retention, high blood sugar, high blood pressure, unusual behavior and mood changes, increased appetite, and weight gain.

For additional safety information, please see the Important Safety Information.

RAYOS is available by prescription only. Your pharmacy should carry RAYOS. In the event they do not have it on the shelf, ask your pharmacist to order it for you. RAYOS can be delivered to your pharmacy, typically within 24 hours. Ask your doctor if RAYOS may be right for you.

RAYOS is the first and only delayed-release form of prednisone. There are generic forms of prednisone, but there is no generic substitute for delayed-release prednisone. RAYOS is different in that only RAYOS releases the anti-inflammatory action of prednisone about 4 hours after taking the tablets.

Prednisone is a type of corticosteroid. Corticosteroids are different from anabolic steroids, which are sometimes used by body builders. Corticosteroids closely resemble hormones that your body produces naturally and are used to help reduce inflammation and pain.

A delayed-release medication postpones the drug effect for an amount of time after you take the dose. With RAYOS, the prednisone dose is released in about 4 hours.

Your doctor will tell you when to take RAYOS. For example, your doctor may ask you to take RAYOS at bedtime. In clinical studies, RAYOS was taken around 10 pm.

RAYOS should be taken once a day. RAYOS tablets should not be broken, divided, or chewed because the delayed release of prednisone depends on a whole tablet. RAYOS is available in 1-mg, 2-mg, and 5-mg tablets. Your doctor will decide what dose is right for you based on your symptoms and will talk to you about when to take it. Your doctor may tell you to take more than 1 pill or a combination of 2 different dose sizes. Always follow the dosing instructions from your doctor.

RAYOS should be taken with food. In a clinical study, RAYOS was taken with a light meal or snack if more than 2.5 hours had passed since the evening meal. RAYOS worked similarly when taken with dinner or with a light meal.

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take RAYOS at the next regularly scheduled time. Do not take an extra dose to make up for the missed dose.

Talk with your doctor before you stop taking RAYOS. You may need to gradually reduce the amount of RAYOS you are taking. Stopping RAYOS suddenly may cause unwanted side effects.

For answers to questions not found on our site, please contact us at 866-479-6742. For answers to questions not found on our site, please contact us at 866-479-6742. For answers to questions not found on our site, please contact us at 866-479-6742.

For any other questions, please contact Product Support at 1-866-479-6742.

IMPORTANT SAFETY INFORMATION

Do not use RAYOS if you are allergic to prednisone.

Long-term use of RAYOS can affect your hormones and one of the ways your body responds to stress. Symptoms, among others, can include weight gain, changes in body appearance (particularly the face), severe fatigue, weak muscles, and high blood sugar. Tell your doctor if you develop any of these symptoms after taking RAYOS.

RAYOS can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Signs and symptoms of infection may be hidden. Tell your doctor if you have had a recent or ongoing infection or if you have been exposed to chickenpox or measles.

RAYOS can cause high blood pressure, salt and water retention, and low blood potassium. Your doctor should monitor these levels.

There is an increased risk of developing perforations in the stomach or intestines if you have certain stomach and intestinal disorders. Signs and symptoms may be hidden.

Behavior and mood changes can occur, including intense excitement or happiness, sleeplessness, mood swings, personality changes, severe depression, and psychosis. Existing conditions may become worse.

Long-term use of RAYOS can cause decreases in bone density. You should talk with your doctor about this risk before you initiate therapy, particularly if you are postmenopausal. Your doctor should monitor bone density with long-term therapy.

RAYOS can cause cataracts, eye infections, and glaucoma. Your doctor should monitor eye pressure if you use RAYOS for more than 6 weeks.

Do not receive a “live” vaccine while taking RAYOS. The vaccine may not work as well during this time, and may not fully protect you from disease. Tell your doctor if you have recently received a vaccine.

Taking RAYOS during pregnancy can harm an unborn baby.

RAYOS may be present in breast milk; discuss the risks and benefits of breastfeeding while taking RAYOS with your doctor.

Long-term use of RAYOS can slow growth and development in children. Children on long-term therapy should be monitored for this.

The most common side effects with RAYOS are water retention, high blood sugar, high blood pressure, unusual behavior and mood changes, increased appetite, and weight gain.

Talk to your doctor before you stop taking RAYOS. You may need to gradually reduce the amount of RAYOS you are taking. Stopping RAYOS suddenly may cause unwanted side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088

The risk information provided here is not comprehensive. To learn more, talk about RAYOS with your healthcare provider or pharmacist. Click here for the full Prescribing Information.

Approved uses of RAYOS

RAYOS, a corticosteroid, is an anti-inflammatory or immunosuppressive agent used in the treatment of many different conditions, such as certain allergic, skin, stomach and intestinal, blood, eye, nerve, kidney, breathing, rheumatologic, and specific infectious diseases or conditions, and organ transplantation. RAYOS is used in the treatment of certain endocrine conditions and to ease the symptoms, including pain, of certain cancer conditions.

For a complete list of indications for RAYOS, please see full Prescribing Information.

IMPORTANT SAFETY INFORMATION

Do not use RAYOS if you are allergic to prednisone.

Long-term use of RAYOS can affect your hormones and one of the ways your body responds to stress. Symptoms, among others, can include weight gain, changes in body appearance (particularly the face), severe fatigue, weak muscles, and high blood sugar. Tell your doctor if you develop any of these symptoms after taking RAYOS.

RAYOS can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Signs and symptoms of infection may be hidden. Tell your doctor if you have had a recent or ongoing infection or if you have been exposed to chickenpox or measles.

RAYOS can cause high blood pressure, salt and water retention, and low blood potassium. Your doctor should monitor these levels.

There is an increased risk of developing perforations in the stomach or intestines if you have certain stomach and intestinal disorders. Signs and symptoms may be hidden.

Behavior and mood changes can occur, including intense excitement or happiness, sleeplessness, mood swings, personality changes, severe depression, and psychosis. Existing conditions may become worse.

Long-term use of RAYOS can cause decreases in bone density. You should talk with your doctor about this risk before you initiate therapy, particularly if you are postmenopausal. Your doctor should monitor bone density with long-term therapy.

RAYOS can cause cataracts, eye infections, and glaucoma. Your doctor should monitor eye pressure if you use RAYOS for more than 6 weeks.

Do not receive a “live” vaccine while taking RAYOS. The vaccine may not work as well during this time, and may not fully protect you from disease. Tell your doctor if you have recently received a vaccine.

Taking RAYOS during pregnancy can harm an unborn baby.

RAYOS may be present in breast milk; discuss the risks and benefits of breastfeeding while taking RAYOS with your doctor.

Long-term use of RAYOS can slow growth and development in children. Children on long-term therapy should be monitored for this.

The most common side effects with RAYOS are water retention, high blood sugar, high blood pressure, unusual behavior and mood changes, increased appetite, and weight gain.

Talk to your doctor before you stop taking RAYOS. You may need to gradually reduce the amount of RAYOS you are taking. Stopping RAYOS suddenly may cause unwanted side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088

The risk information provided here is not comprehensive. To learn more, talk about RAYOS with your healthcare provider or pharmacist. Click here for the full Prescribing Information.

Approved uses of RAYOS

RAYOS, a corticosteroid, is an anti-inflammatory or immunosuppressive agent used in the treatment of many different conditions, such as certain allergic, skin, stomach and intestinal, blood, eye, nerve, kidney, breathing, rheumatologic, and specific infectious diseases or conditions, and organ transplantation. RAYOS is used in the treatment of certain endocrine conditions and to ease the symptoms, including pain, of certain cancer conditions.

For a complete list of indications for RAYOS, please see full Prescribing Information.